Doxee

Manufacturer: Alto
Category: Skin
Substance: Doxycycline
Package: 100mg (30 capsules)

Doxycycline Doxee is a semisynthetic tetracycline antibiotic with a broad spectrum of activity, it has a bacteriostatic effect. Penetrating into the cell, acts on intracellularly located pathogens. Inhibits the synthesis of proteins in the microbial cell, disrupting the association of transport aminoacyl ribonucleic acids with the 30S subunit of the ribosomal membrane. In vitro doxycycline is active against gram-positive microorganisms - Staphylococcus spp. (including Staphylococcus aureus, Staphylococcus epidermidis), Streptococcusspp. (including Streptococcuspneumoniae), Clostridiumspp., Listeriaspp .; and gram-negative microorganisms - Neisseriagonorrhoeae, Neisseriameningitidis, Haemophilusinfluenzae, Klebsiellaspp., Entamoebahistolytica, Escherichiacoli, Enterobacter, Salmonellaspp., Yersiniaspp. (formerly Pasteurella spp.), Bacteroides spp., Treponema spp. (including strains resistant to other antibiotics, for example, modern penicillins and cephalosporins). The most sensitive Haemophilus influenzae (91-96%) and extracellular parasites. Doxycycline is active against most pathogens of especially dangerous and dangerous infectious diseases: plague (Y.pestis), tularemia (Francisella tularensis), anthrax (Bacillus anthracis) microbes, cholera vibrio (V.cholerae), Rickettsia spp. brucellosis (Brucella spp.), causative agents of glanders, ornithosis, psittacosis, legionella, trachoma, venereal granuloma (Chlamidia pneumoniae, Chlamydia trachomatis. Chlamydia granulomatosis). It acts on most strains of Proteus, Pseudomonas aeruginosa and fungi. Doxycycline surpasses natural tetracyclines in the degree of antibacterial activity. Unlike tetracycline and oxytetracycline, it has a higher therapeutic efficacy even with the introduction of 10 times smaller doses and a longer duration of action. To a lesser extent than other antibiotics of the tetracycline series, it inhibits the intestinal flora, differs from them by more complete absorption and a longer duration of action. There is cross-resistance to other tetracyclines, as well as penicillins.

Doxee Indications

Infectious and inflammatory diseases caused by susceptible microorganisms: respiratory tract infections (pharyngitis, acute and chronic bronchitis, tracheitis, bronchopneumonia, lobar pneumonia, lung abscess, pleural empyema). Infections of the upper respiratory tract (otitis, tonsillitis, sinusitis, etc.). genitourinary system (cystitis, pyelonephritis, prostatitis, urethritis, urethrocystitis, urogenital mycoplasmosis, endometritis, endocervicitis, acute orhiepididymitis. Gonorrhea). Infections of the biliary tract and gastrointestinal tract (cholecystitis, holangitis). roenterokolit, bacillary dysentery, diarrhea, travelers). Skin and soft tissue infections (cellulitis, abscesses, furunculosis, panaritiums, infected burns, wounds, etc.). Infectious eye diseases, syphilis, yaws, yersiniosis, legionellosis, rickettsiosis, chlamydia of various localization (including Prostatitis and proctitis) , fever ku, spotty fever of rocky mountains, typhoid fever (including loose, tick-borne, relapsing), lime disease (i st. Erythema migrans), bacillary and amebic dysentery, tularemia, cholera, actinomycosis, malaria. As part of combination therapy, leptospirosis, trachoma, psittacosis, ornithosis, granulocytic ehrlichiosis. Whooping cough, brucellosis, osteomyelitis. Sepsis, subacute septic endocarditis, peritonitis. Prevention of postoperative purulent complications. Plasmodium falciparum malaria during short-term travels (less than 4 months) in an area where chloroquine and / or pyrimethamine-sulfadoxine-resistant strains are common. Patients under 65 are prescribed as a first-line drug for exacerbation of chronic bronchitis (including Against the background of bronchial asthma) without comorbidities (these exacerbations are often caused by haemophilus influenzae). Effective in exacerbation of bronchopulmonary infections (usually staphylococcal etiology) in patients with cystic fibrosis, chlamydial arthritis, granulocytic ehrlichiosis. In elderly patients, it is used to treat acute prostatitis and urinary infection caused by escherichia coli.